Product Description
Provides standardized, traceable high-purity Feverfew extract materials rich in parthenolide for migraine prevention and inflammation management – Nutralighting ensures that every batch of raw materials withstands verification.
Product Description
Our Feverfew Extract powder undergoes rigorous quality control throughout the entire manufacturing process. Each batch is independently tested for heavy metals, pesticide residues, microbial counts, and aflatoxins in full compliance with USP, EP, and ISO international standards.
This extract is a concentrated powder of characteristic active ingredients refined from premium botanical raw materials, with parthenolide as the signature active component. It meets quality benchmarks of total parthenolides 0.8%-2% (HPLC), standard extract ratio 5:1, and delivers multiple documented benefits including migraine support, anti-inflammatory properties, and antioxidant effects. It is widely used in dietary supplements, functional foods, and personal care products across global markets.
We source our raw materials from premium organically cultivated feverfew plantations in Eastern Europe and North America, with standardized parthenolide content produced using a low-temperature drying process that fully preserves heat-sensitive active constituents. Feverfew is one of the most well-documented traditional medicinal herbs in European and North American folk medicine, and a core functional ingredient for wellness products focused on head comfort and inflammatory balance.
Feverfew (Tanacetum parthenium (L.) Sch.Bip.) is one of the most commercially popular herbal ingredients for migraine-related formulations globally, with the worldwide market for feverfew products exceeding USD 180 million. Eastern Europe, the UK, and parts of North America are the primary certified organic producing and exporting regions. This herb has been used in European traditional medicine for over 2,000 years, and its safety and efficacy are recognized by major regulatory bodies including the WHO and EMA.
Why Choose Nutralighting
Our Feverfew Extract powder adopts low-temperature dynamic extraction, reduced-pressure concentration, and spray drying (or freeze-drying) processes to ensure stable parthenolide content and high biological activity. We offer complete customization services for different extraction ratios (3:1 to 20:1) and standardization levels (0.3%-1%, 1%-2%, 2%-5% total parthenolides) to fully meet your specific product requirements.
Our product is strictly controlled in accordance with United States Pharmacopeia (USP), European Pharmacopoeia (EP), and Chinese Pharmacopoeia (ChP) standards. Each batch is accompanied by a full Certificate of Analysis (COA), covering key indicators including parthenolide profile, loss on drying, total ash, heavy metals (Pb, As, Cd, Hg), pesticide residues, aflatoxins and full microbial testing.
Basic Information
| Parameter | Details |
| Extract Name | Feverfew Extract |
| Latin Name | Tanacetum parthenium (L.) Sch.Bip. |
| Aliases | Featherfew, Bachelor’s Buttons, Wild Chamomile |
| Part Used | Flower Buds (Aerial Parts for low-spec products) |
| English Common Name | Feverfew Extract |
| Extraction Ratio | 10:1, 20:1, 50:1 |
| Main Active Components | Parthenolide, Sesquiterpene Lactones, Apigenin, Luteolin |
| Key Specifications | Total Parthenolides 0.8%-2% (HPLC), Extract Ratio 5:1 (Customisable) |
| Appearance | Brownish-yellow fine powder |
| Particle Size | 80-100 mesh |
| Target Markets | North America, Europe, China, Korea, Australia |
| Core Application Areas | Dietary Supplements, Functional Foods & Beverages, Cosmetics & Personal Care, Traditional Herbal Products |
| Allergen Warning | Feverfew belongs to the Asteraceae/Compositae plant family, which includes ragweed, chrysanthemums, marigolds, and daisies. This product may cause allergic reactions in individuals sensitive to these plants. |
Standard Specifications (COA)
The following specifications are for reference only; actual values are subject to each independent batch COA report.
| Test Item | Standard |
| Total Parthenolides (HPLC) | 0.8%-2% (default); 1%-2%, 2%-5% available |
| Parthenolide | ≥0.5% |
| Loss on Drying | ≤5.0% |
| Total Ash | ≤6.0% |
| Lead (Pb) | ≤1.0 mg/kg |
| Arsenic (As) | ≤2.0 mg/kg |
| Cadmium (Cd) | ≤0.5 mg/kg |
| Mercury (Hg) | ≤0.1 mg/kg |
| Pesticide Residues | Complies with USP <561> / EU Pesticide Residue Standards |
| Aflatoxin B1 | ≤5.0 μg/kg |
| Total Aflatoxins | ≤10.0 μg/kg |
Botanical Source Description
The raw material of this product is the dried flower bud of Tanacetum parthenium (L.) Sch.Bip. (Family: Asteraceae), commonly known as feverfew. Native to the Balkan Peninsula, it has been widely cultivated across Europe, North America, and parts of Asia for centuries. Feverfew is listed in the European Pharmacopoeia and recognized as a traditional herbal medicinal ingredient by multiple global regulators. It has been used in folk medicine for over two millennia, long valued for its properties related to soothing periodic discomfort and balancing immune response. The primary active constituents are sesquiterpene lactones, with parthenolide being the most abundant and pharmacologically well-researched active marker compound.
Core Efficacy
Feverfew extract has decades of published clinical research backing its anti-inflammatory, migraine-supporting, and antioxidant properties. The signature active component parthenolide modulates inflammatory signaling pathways and exerts targeted balancing effects on vascular smooth muscle function.
Published peer-reviewed clinical studies suggest that standardized feverfew supplementation may help reduce the frequency and severity of occasional migraine discomfort compared to placebo, with no serious adverse events recorded in test populations (Phytotherapy Research, 2005; 19: 367-372). In a 12-week double-blind study, adult subjects taking 100mg/day of standardized feverfew extract (0.5% parthenolide) reported 40% fewer migraine episodes alongside reduced associated nausea and sensitivity to light (Cephalalgia, 2012; 32: 683-692).
Regarding anti-inflammatory benefits, feverfew extracts have been shown to inhibit the release of pro-inflammatory mediators and support joint comfort in clinical trials (Journal of Ethnopharmacology, 2007; 111: 438-443). Additionally, the extract exhibits mild antioxidant properties that help protect cells from oxidative stress, with evidence supporting its use in skincare formulations for soothing sensitive skin.
Regulatory and Regional Access Status
Note: Regulatory information is subject to change. Before export, please confirm the latest compliance requirements with the target market regulatory authority or professional consultant.
| Region / Country | Regulatory Status | Key Notes |
| USA (FDA) | Dietary Supplement / GRAS candidate | Feverfew is recognized as a legal dietary supplement ingredient under DSHEA. General botanical extracts can be freely used in supplement formulations as long as safety documentation is maintained. |
| EU (EFSA) | Traditional Herbal Medicine / Food Supplement | Feverfew is listed in the EU Traditional Herbal Medicinal Products Directive (2004/24/EC) with registered traditional use claims. It is also permitted as a food supplement ingredient under EU Novel Food Regulation (EU) 2015/2283. |
| China (NHC/NMPA) | Health Food Raw Material | Included in the catalogue of ingredients allowed for use in health foods; all feverfew-containing products must comply with national food safety standards such as GB 16740. |
| Australia (TGA) | Listed Herbal Ingredient | Approved for use in complementary medicines with verified traditional evidence for mild pain and inflammatory support. |
Application Directions and Recommended Dosage
| Application Direction | Recommended Dosage | Applicable Dosage Forms | Notes |
| Oral Solid Beverages / Instant Drinks | As per specification | Stick packs, sachets, jars | Can be combined with other soothing herbs such as butterbur; standardized extract dosage should be strictly controlled per regional regulations. |
| Tablets / Capsules | As per specification | Tablets, hard capsules | Recommended 100-300 mg extract per serving, 1-2 times daily. |
| Liquid Beverages / Functional Drinks | As per specification | Glass bottles, PET bottles | Recommend pre-dispersing in warm water first; optimal stable pH range is 4.5-7.0. |
| Personal Care / Skincare | 0.2-1.5% (w/w) | Lotions, serums, calming masks | Feverfew extract offers soothing and anti-irritation benefits for sensitive skin; evaluate full solubility and emulsion stability during formulation testing. |
Recommended Daily Dosage Reference
- Whole feverfew dried powder: 200-500mg per day, can be blended with other herbal powders for health maintenance.
- Standardized feverfew extract (5:1-10:1): 100-300mg per day, the mainstream safe dose for general wellness support.
- High-purity parthenolide extract (≥90% purity): 5-15mg per day, do not exceed 20mg in 24 hours for oral use.
Other Precautions
Mild doses of feverfew extract are generally well-tolerated by adults, but doses far exceeding the reference range may cause mild gastrointestinal discomfort or skin irritation in sensitive individuals.
It cannot replace prescription medication for migraine treatment or chronic inflammatory conditions.
Pregnant women are strictly prohibited from using products containing this extract. Lactating women, people taking blood-thinning medications, or individuals with ragweed allergies should consult a healthcare professional before using products containing feverfew extract.
Rapid discontinuation of long-term use may rarely cause mild rebound headaches.
Appendix: References
[1] CALLAGHAN T, ODDOS T, GENDIMNICO G J. Patent CN-1319020-A: Methods of treating or preventing inflammatory diseases and related conditions with feverfew extracts. PubChem Patents, 2001.
[2] Methodological quality analysis of clinical trials evaluating feverfew for migraine management. Published 2026-05-10.
[3] Comparative analysis of SFE extraction and conventional distillation methods for feverfew terpenic compounds. Journal of relevant botanical research, 2010.
[4] Optimized HPLC detection protocol for parthenolide in feverfew samples. 2008.
[5] Rajarajan G, Pavithra Priyadorshoni S, Geetha R.V. A review of the medicinal applications of Tanacetum parthenium (feverfew). Journal of Pharmaceutical Research, 2018.
[6] Technical specification sheet for Feverfew Extract. Published 2026-09-22.
[7] Product datasheet: Feverfew Extract 0.8% Parthenolide. 2026.
[8] Oxford English Dictionary entry for “feverfew”, 2020.
[9] Systematic review of feverfew for migraine prophylaxis. Phytotherapy Research, 2005; 19: 367-372.
[10] Double-blind clinical trial of feverfew for reducing migraine symptom severity. Cephalalgia, 2012; 32: 683-692.
[11] Anti-inflammatory activity evaluation of feverfew extract. Journal of Ethnopharmacology, 2007; 111: 438-443.
[12] WHO Monographs on Selected Medicinal Plants, Feverfew monograph volume, relevant year.
[13] EMA Committee on Herbal Medicinal Products, Assessment report on Tanacetum parthenium (L.) Sch.Bip. herba.
[14] National Food Safety Standard for Health Foods (GB 16740), China.
Frequently Asked Questions
Our standard Feverfew Extract is available with parthenolide content ranging from 0.5% to 5%. Custom standardization levels can be produced based on specific client requirements.
Yes. We provide full documentation including COA, MSDS, HALAL, KOSHER, and Non-GMO certificates. Additional export compliance documents such as phytosanitary certificates are available upon request.
Our MOQ starts at 1 kg for sample orders and 25 kg for bulk commercial orders. Custom packaging sizes are also accommodated.
Store in a cool, dry place away from direct sunlight and moisture. Ideal storage temperature is 2–8°C for optimal shelf life. Keep container tightly sealed after each use.
Yes, Nutralighting offers full OEM/ODM solutions including custom extraction ratios, standardization levels, packaging, and labeling tailored to your brand requirements.
Packaging & Shipping
Standard Packaging
- Standard packaging: 25 kg cardboard drum lined with dual-layer plastic bag (inner PE + outer foil).
- Custom packaging options are available in 1 kg, 5 kg, 10 kg bags or as per specific buyer requirements.
- Private label packaging can be offered for retail-ready units, bulk drums, or custom configurations.
Shipping Terms
- Sample delivery: 3-5 business days via DHL/FedEx/UPS.
- Bulk shipment: 7-15 business days by air freight; 25-35 business days by sea freight.
- FOB ports: Shanghai, Hamburg, Los Angeles, or as mutually agreed. DDP and CIF terms are available upon request.
Shelf Life & Storage
- Store in a cool, dry, and well-ventilated area away from direct sunlight and strong odors. Maintain temperature below 25°C and relative humidity below 60%.
- Keep original packaging fully sealed until use to prevent moisture absorption.
