Formulated for joint health and exercise recovery, providing standardized, traceable bitter principles / triterpene high-purity holly extract raw material – Nutralighting ensures every batch of raw material can withstand verification.

Product Description

The holly extract product uses bitter principles and triterpenes as the core standard components, sourced from genuine holly leaves in Hubei, with a stable and controllable 10:1 extraction ratio. Its core positioning is joint health and exercise recovery – the main active ingredient, salicylate derivatives, is converted into salicylic acid in the body, inhibiting the COX-2 inflammation pathway and exhibiting anti-inflammatory and analgesic effects similar to aspirin.  It supports functions such as joint health, inflammation management, and exercise recovery, suitable for health foods, functional foods, and personal care development.

Holly leaves are commonly used heat-clearing and detoxifying herbs in southern regions, with Hubei and Hunan as main production areas.

Basic Information

Why Choose Nutralighting

• Standardized Extract: 10:1 extraction ratio specification (bitter principles / triterpenes), derived from authentic Hubei holly leaves, with stable batch consistency.
• As a trusted B2B natural-ingredient supplier, Nutralighting provides competitive pricing, reliable lead times, and dedicated trade support for international orders. Bulk and private-label packaging options are available upon request.

Standard Specifications (COA)

The following specifications are for general reference; the specific COA report for each batch shall prevail.

Plant Raw Material Introduction

This product’s raw material is the dried leaves of the Aquifoliaceae plant Ilex pubescens Thunb. Mainly produced in provinces south of the Yangtze River. Holly leaves are an important herb in Traditional Chinese Medicine for clearing heat and cooling the blood, recorded in the “Chinese Materia Medica.”

Core Efficacy

The following efficacy overview is based on published scientific research and traditional use; specific efficacy should be comprehensively assessed in combination with product form and dosage.

[Main Efficacy Overview] Holly extract has a traditional basis for use in joint health and pain relief. Its main active component, salicin, is converted into salicylic acid in the body, providing anti-inflammatory and analgesic effects similar to aspirin. Holly berry extract is rich in polyphenolic compounds, exhibiting antioxidant and anti-inflammatory properties. In North American traditional medicine, holly leaves and bark have been used to relieve arthritis pain and fever. Modern studies show that its extract can inhibit the COX-2 inflammatory pathway.

Regulatory and Regional Access Status

The following information is compiled based on publicly available regulatory data; actual market access should be subject to the latest regulations of the target country.

Application Directions and Recommended Dosage

Recommended Daily Dosage Reference

• General Health Use: Use according to product specifications and the dosage recommended by the formulator
• Personal Care and Skincare: The amount added in formulations depends on the specific product, recommended 0.1~2.0%

Other Notes

• Contraindicated for pregnant women: The blood-activating and stasis-resolving properties of Maodongqing may stimulate uterine contractions, increasing the risk of miscarriage and premature birth, and posing a serious threat to the health of both the mother and the foetus.
• Use with caution during menstruation: As women are already experiencing bleeding during their period, taking Maodongqing may increase the volume of bleeding, leading to prolonged periods, menstrual irregularities and other issues, which are detrimental to menstrual health.
• Contraindicated for patients with low blood pressure: Maodongqing has a certain blood-pressure-lowering effect; in individuals with low blood pressure, taking it may further lower blood pressure, potentially causing symptoms of hypotension such as dizziness, fatigue and blurred vision, and in severe cases, may lead to fainting.
• Contraindicated for patients with haemorrhagic disorders: For individuals suffering from haemorrhagic disorders such as gastric ulcer bleeding, cerebral haemorrhage or haemophilia, taking Maodongqing may exacerbate bleeding and may even trigger severe, life-threatening haemorrhage.

Appendix: References

(The following references are for technical reference purposes; some are open access and can be accessed via PubMed/PMC or the journal’s official website)

[1] ‘Chinese Materia Medica’ (Holly Standard)

[2] Journal of Ethnopharmacology, 2020: Ilex pubescens hemostatic effects

[3] Pharmaceutical Biology, 2019: Ilex leaf antioxidant activity

[4] Chinese Journal of Ethnomedicine, 2021