Anti-Fatigue and Immune Modulation North American Ginseng – Standardized Extract of American Ginseng (Panax quinquefolius)

Product Description

American Ginseng Extract is made from the dried roots of Panax quinquefolius of the Araliaceae family, concentrated primarily on ginsenosides (mainly Rb1 and Rc) as the main active components. It meets a ginsenoside content standard of 10%-20% (HPLC). Due to its anti-fatigue, immune modulation, and cognitive support properties, it is widely used in health foods, functional foods, and personal care products.

American ginseng is a traditional North American herbal medicine, with Wisconsin, USA being the traditional major production area. In recent years, its application in the Chinese health product market has grown rapidly.

Why Choose Nutralighting

• Potent Ginsenoside Profile: Standardized to Rb1, Rg1, and total ginsenosides for consistent bioactivity
• Source: Sourced from certified wild-crafted or cultivated Panax quinquefolius roots
• Clean Label Friendly: Available in solvent-free or food-grade extraction formats

Basic Information

Standard Specifications (COA)

The following specifications are conventional reference values; the specific values are subject to the COA report of each batch.

Introduction to Plant Raw Material

The raw material of american ginseng extract powder product is the dried root of the Araliaceae plant American ginseng, Panax quinquefolius L. It is mainly produced in Wisconsin and Michigan in the United States, as well as in Canada, and has also been introduced and cultivated in Shandong and Jilin provinces in China. It has a cool nature and a sweet slightly bitter taste, and it enters the lung, heart, and kidney meridians.

Traditionally, it is used for tonifying Qi and nourishing Yin, and for daily maintenance related to clearing heat and generating fluids. The main active components are ginsenosides, mainly Rb1 and Rc.

Core Benefits

American ginseng (Panax quinquefolius) extract has a traditional application basis and research value in antifatigue and immune modulation. Its core active components, ginsenosides (mainly Rb1 and Rc), are involved in the regulation of energy metabolism and stress adaptation in the body; American ginseng polysaccharides help support immune activity. Related clinical studies can be found in the literature (Journal of Ethnopharmacology, 2014). Specific effects need to be evaluated in combination with formulation and dosage.

Regulatory and Regional Access Status

The following information is compiled based on publicly available regulatory data; actual market access should be confirmed according to the latest regulations of the target country.

Application Directions and Recommended Dosage

Recommended daily dosage reference

• The recommended daily dose for general adult health maintenance is approximately 3-6 grams (Data based on American ginseng roots); it may be taken with warm water or incorporated into pills or powders.
• It is recommended not to take American ginseng extract for more than two weeks at a time; after this, discontinue use for one to two weeks before considering resuming, to avoid long-term continuous use.
• It is best taken in the morning on an empty stomach or half an hour before a meal; taking it before bed may affect the quality of sleep at night.

Other Precautions

• Under no circumstances should american ginseng extract product be taken in conjunction with traditional Chinese medicines such as Li Lu or Wu Ling Zhi, as this may cause nausea or palpitations, or negate the qi-tonifying effects.
• Do not eat radishes or drink strong tea or coffee within two hours of taking american ginseng extract product, to avoid affecting the absorption of the active ingredients.
• American ginseng extract product must not be taken by individuals with spleen yang deficiency (characterised by sensitivity to cold), those with chronic sticky stools, or those in the acute phase of a cold, fever or other infection.
• Individuals currently taking anticoagulants, antidiabetic medicines or immunosuppressants must consult a doctor before use.
• Pregnant women, breastfeeding women, children and those with severe liver or kidney impairment are advised not to take american ginseng extract product without medical advice.

Appendix: References

[1] Chen L.L. et al., Journal of Ethnopharmacology, 2014; 154: 583-590.

[2] Lee M.S. et al., Journal of Korean Medicine, 2007; 28: 1-10.

[3] Sherrill C.L. et al., Journal of Alternative and Complementary Medicine, 2012; 18: 1062-1068.

[4] Wang Y, Choi HK, Brinckmann JA, et al. Chemical analysis of Panax quinquefolius (North American ginseng): A review[J]. Journal of Chromatography A, 2015, 1426: 1-15.

[5] Vuksan V, Xu ZZ, Jovanovski E, et al. Efficacy and safety of American ginseng (Panax quinquefolius L.) extract on glycemic control and cardiovascular risk factors in individuals with type 2 diabetes: A double-blind, randomized cross-over clinical trial[J]. European Journal of Nutrition, 2019, 58: 1237-1245.

[6] Bell L, Fança-Berthon P, Cozannet RL, et al. Effects of American ginseng (Panax quinquefolius) extract on human neurocognitive function: a review[J]. Nutritional Neuroscience, 2026, 29(2): 213-223.