Product Description
Provides standardized, traceable Nux Vomica (Strychnos nux-vomica) extract with controlled toxic components for raw materials that require strict compliance management in promoting blood circulation and removing stasis – Nutralighting ensures that every batch of raw materials can withstand verification.
Product Description
Nux Vomica (Strychnos nux-vomica) is the dried seed of plants from the Loganiaceae family, traditionally used to promote blood circulation, remove stasis, dredge channels, and relieve pain. This product contains strychnine, brucine, and other Strychnos-type alkaloids, which are highly toxic and must be used under professional guidance with strictly controlled dosages. It is suitable for pharmaceuticals and topical formulations under regulatory control.
Nux Vomica Extract (Nux Vomica Extract / Strychnos Extract) is a strictly standardized, traceable Strychnos-type alkaloid raw material, with strychnine and brucine as the core active components. The alkaloid content is controlled (0.5%-2% calculated as brucine). Traditionally used for promoting blood circulation, removing stasis, and dredging channels to relieve pain; due to the strong toxicity of the alkaloids, dosage must be strictly controlled under professional guidance. Suitable for pharmaceuticals and topical formulations subject to strict regulatory control.
Nux Vomica is a traditional Chinese medicinal material used to promote blood circulation and remove stasis. It is mainly produced in India and Vietnam, with stable cultivation and supply domestically and internationally. Nux Vomica preparations are primarily used for rheumatic pain and trauma treatment, and must be used strictly according to medical instructions.
Basic Information
| Item | Content |
| Extract Name | Nux Vomica Extract |
| Alias | Nux Vomica (another name) |
| Common English Name | Strychnos Extract / Dark-leaved Strychnos Extract |
| Main Components | Strychnine, Strophanthin |
| Main Specifications | Strychnine 0.5%-2% |
| Target Market | China (strictly regulated) |
| Core Application Areas | Traditional blood circulation promotion and blood stasis removal; meridian dredging and pain relief; strict compliance management |
Standard Specifications (COA)
The following specifications are for general reference; the specific values are subject to the COA report of each batch.
| Testing Items | Standards |
| Strychnine | Strychnine 0.5%-2% |
| Loss on Drying | ≤5.0% |
| Total Ash | ≤6.0% |
| Lead (Pb) | ≤1.0 mg/kg |
| Arsenic (As) | ≤2.0 mg/kg |
| Cadmium (Cd) | ≤0.5 mg/kg |
| Mercury (Hg) | ≤0.1 mg/kg |
| Pesticide Residues (Organochlorine/Organophosphorus) | Complies with USP <561> |
| Aflatoxin B1 | ≤5.0 μg/kg |
| Total Aflatoxins | ≤10.0 μg/kg |
| Total Microbial Count (TAMC) | ≤1×10⁴ CFU/g |
| Yeast and Mold (TYMC) | ≤1×10² CFU/g |
| Escherichia coli | Not detected (1g) |
| Salmonella | Not detected (1g) |
Introduction to Plant Material
The raw material of this product is the dried mature seeds of Strychnos nux-vomica L., a plant of the Loganiaceae family. It is mainly produced in India, Vietnam, Thailand, and regions of Yunnan and Guangdong in China. It is recorded in Volume I of the 2020 edition of the Pharmacopoeia of China. Strychnine is its characteristic and highly toxic alkaloid, while brucine, also an alkaloid of the Strychnos type, is similarly toxic; both have very narrow therapeutic windows and require strict processing and dosage control.
Core Functions
Strychnos nux-vomica is used in traditional medicine to promote blood circulation, remove blood stasis, unblock the channels, and relieve pain, often as an adjunct treatment for rheumatic pain and injuries from falls or trauma.
Modern research shows that its alkaloids (strychnine and brucine) have central nervous system stimulant, analgesic, and anti-inflammatory activities, with mechanisms related to glycine receptor antagonism and regulation of motor neuron excitability.
Special attention is required: strychnine has an extremely narrow therapeutic window and high toxicity; overdose can cause severe toxic reactions such as tetanic convulsions, so the use must be strictly controlled under professional guidance, with monitoring of medication safety.
Specific efficacy and safety need to be assessed in combination with dosage form, dose, and applicable regulations.
Regulatory and Regional Access Status
The following information is compiled from publicly available regulatory data; actual market access should be based on the latest regulations in the target country.
| Region/Country | Regulatory Status | Key Notes |
| United States (FDA) | Dietary Supplement / GRAS | If it is a plant extract, it is generally regulated as a dietary supplement; some ingredients have already received GRAS recognition (specific cases need to be confirmed individually). USP has included monographs for various extracts. |
| China (NHC/NMPA) | Health food raw materials / Novel foods | According to the 2020 edition of the Chinese Pharmacopoeia and standards such as GB 16740; some varieties are already listed in the health food raw materials catalog or in the catalog for use in ordinary foods, and the latest regulatory status of each variety needs to be specifically verified. |
Application Directions and Recommended Dosage
| Application direction | Recommended addition amount | Applicable dosage forms | Remarks |
| Professional / External formulation (strictly controlled dosage) | Determined according to product specifications | Capsules, topical formulations | Must be used under compliance and professional guidance, with strict dose control |
| Pain management formula | According to product specifications | Capsules, topical formulations | Recommended addition of topical formulations 0.5~2% |
| Oral solid beverages / instant powders | According to specifications | Stick packs, bags, cans | Can be compounded with other functional ingredients, recommended to control the amount using standardized extracts |
| Tablet Candy / Capsules | According to specifications | Tablets, Hard Capsules | Each capsule recommended to contain 250~500 mg of extract, 2~3 times daily |
| Oral Liquid / Functional Drinks | According to specifications | Glass bottles, PET bottles | It is recommended to disperse in warm water before adding to the system, pay attention to pH stability |
| Personal Care Skincare Products | 0.1~2.0%(w/w) | Lotion, Essence, Mask | Solubility and stability need to be evaluated based on the formulation system |
Recommended Daily Dosage Reference
- General Health Use: Use according to product specifications and the dosage recommended by the formulator
- Personal Care and Skincare: The amount added in the formulation depends on the specific product, recommended 0.1~2.0%
- Compliance and Safety: Stenning is a controlled toxic ingredient. Export and formulation use must comply with the regulations, dosage limits, and safety management requirements of the target country.
Other Precautions
Nux Vomica Extract is highly toxic and must be used under professional guidance with strictly controlled dosages.
Appendix: References
(The following references are for technical reference, some are open access and can be accessed via PubMed/PMC or journal official websites)
[1] Wang Y. et al., Journal of Ethnopharmacology, 2014; 156: 283-289.
[2] Hu H.W. et al., Journal of Ethnopharmacology, 2004; 93: 285-290.
[3] Chinese Pharmacopoeia Commission, Chinese Pharmacopoeia 2020, Part I: 36.
Frequently Asked Questions
Our standard MOQ is 1kg for sample orders and 25kg for bulk orders. Custom MOQ can be discussed for large-volume procurement.
Yes, we provide organic, KOSHER, HALAL, and non-GMO certification documents upon request for applicable batches.
Yes, we support customization of extraction ratio, active component content, and packaging to meet specific B2B requirements.
We maintain strict raw material sourcing controls and use standardized extraction processes. Each batch is tested against the same COA standards to ensure consistency.
Yes, we provide complete export documentation including COA, MSDS, phytosanitary certificates, and country-specific compliance documents. However, buyers should verify local import regulations for controlled botanical ingredients.
Packaging & Shipping
Standard Packaging
- Standard packaging: 1kg aluminum foil bag inside 25kg fiber drum or cardboard drum. Custom packaging available per buyer requirements. Each unit labeled with product name, batch number, manufacturing date, and expiry date.
Shipping Terms
- Ships worldwide via express (DHL/FedEx/UPS), air freight, or sea freight depending on order volume. Documentation includes commercial invoice, packing list, COA, MSDS, and phytosanitary certificate. Lead time: 7-15 working days after order confirmation.
Shelf Life & Storage
- Store in a cool, dry, and well-ventilated place, protected from light and moisture. Avoid exposure to high temperatures during storage and transit. Shelf life: 24 months from production date.
